Yersinia pathology

 


GRANULOMATOUS LYMPHADENITIS.
Lymph node from a 55-year-old woman with erythema nodosum and acute myocarditis. Two small granulomas consisting of epitheloid cells and Langhans type of giant cells are seen. H-E x 150.


CHRONIC MESENTERIC LYMPHADENITIS.
Low-power view of histological section of lymph node from a 41-year-old man who presented with tumorous mesenteric lymphadenitis. There is considerable fibrosis with thickening of the capsule and the trabeculae with a relative reduction in the number of lymphocytes.


COMPRESSION OF THE INFERIOR VENA CAVA.
A 60-year-old male was admitted with a clinical condition resembling lymphogranulomatosis. Cavography showed compression of the inferior veana cava, most possibly caused by enlarged lymph nodes.


ULCERATIVE COLITIS.
A 32-year-old man was admitted 7 months after the acute onset of severe diarrhea. He later underwent colonic resection. The microphotograph shows the superficial part of the large bowel mucosa. There is a chronic inflammatory infiltrate in the lamina propria. The crypt epithelium shows some regenerative changes, and there is a crypt abscess. These alterations are compatible with the diagnosis of ulcerative colitis.


FULMINANT COLITIS.
Colonic specimen from a 20-year-old man who underwent proctocolectomy because of fulminant colitis.There is hemorrhage in the lamina propria and dilated vessels in the deeper part of the mucosa. Conspicuous lymph nodes, lymphocytes and a few reticulum cells can be seen in the submucosa.


LIVER INVOLVEMENT.
Liver biopsy from a 59-year-old woman. The portal tract seen to the left is moderately enlarged with diffuse infiltration of lymphocytes. A short connective tissue septum invades the surrounding parenchyma. The parenchymal cells vary in size and form and the liver plates are difficult to distinguish without a silver stain. The Kupffer cells tend to form small clusters.


MALIGNANT MESOTHELIOMA.
This biopsy specimen from a tumor of the right pleura of a 61-year-old woman shows partly spindle shaped, partly more polygonal and epitheloid cells. The cells showed strong immunereactivity for cytokeratins (AE1/AE3), supporting the mesothelial nature of the tumor.

EMERGENCY SURGERY REVEALING ACUTE TERMINAL ILEITIS.

 


OBSERVED AND EXPECTED SURVIVAL RATES.
Regarding the whole material, the difference between the observed and expected cumulative survival rates remained significant for 8 years (0.9189 < 0.9456; p < 0.025).

 

The author expresses his gratitude to the following departments for examination and microphotographs of biopsy speciments:
  1. Department of Pathology, The National Hospital (Rikshospitalet), University of Oslo.
  2. Department of Pathology, The Gade Institute, University of Bergen.
  3. Department of Pathology, Aker Hospital, University of Oslo.